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Cyclooxygenase inhibitory activity of South African plants used against inflammation

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New Orleans Med Surg J ; 94 : Evaluation of the genotoxic activity and acute toxicity of Euphorbia splendens latex, a molluscicide for the control of schistosomiasis. Braz J Med Biol Res ; 24 : Evaluation of the mutagenicity of the molluscicidal latex of Christ's Crown Euphorbia milii var. Mutat Res ; : 15 Antitumor agents, Kansuiphorins A and B, two novel antileukemic diterpene esters from Euphorbia kansui.

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Chem Pharm Bull Tokyo ; 39 : New antitumor principles, casearins A-F, for Casearia sylvestris Sw. Chem Pharm Bull Tokyo ; 38 : Inhibition of topoisomerase I function by nitidine and fagaronine. Chem Res Toxicol ; 6 : Identification of novel topoisomerase I inhibitors. Proc Am Assoc Cancer Res ; 35 : Chelerythrine and sanguinarine alkaloids induce membrane translocation and irreversible inactivation of protein kinase C by modifying thiol residues. Wolff J, Knipling L. Antimicrotubule properties of benzophenanthridine alkaloids.

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Molecular toxicology of pyrrolizidine alkaloids. Diss Abstr Int [B] ; 55 : Phase II trial of indicine N -oxide in relapsed pediatric solid tumors. A report from the children's cancer study group. Invest New Drugs ; 9 : Phase II trial of indicine N -oxide in relapsed acute leukemia of childhood. Am J Clin Oncol ; 15 : Feasibility of a high-flux anti-cancer drug screen using a diverse panel of cultured human tumor cell lines.

New drug development. Thoracic Oncology.


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  • Philadelphia: Saunders, Development of human tumor cell line panels for use in disease-oriented drug screening. Prog Clin Biol Res ; : Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm. J Natl Cancer Inst ; 81 : In vitro antioxidant and cytotoxic activity of extracts of Baccharis cordifolia DC.

    Cyclooxygenase inhibitory activity of South African plants used against inflammation

    J Ethnopharmacol ; 58 : Cytotoxic constituents of Baccharis gaudichaudiana. J Nat Prod ; 57 : In vitro cytotoxicity of a series of quassinoids from Brucea javanica fruits against KB cells. Planta Med ; 57 : 62 Biochem Pharmacol ; 43 : Effect of antioxidants on radical intensity and cytotoxic activity of eugenol. Anti-cancer Res ; 18 : Ann Oncol ; 5 suppl 8 : Purification and partial characterization of a mitogenic lectin from the latex of Euphorbia marginata.

    Biochim Biophys Acta ; : 33 Dittrich H, Kutchan TM.